These diseases are collectively called MYH9-related diseases (MYH9RD) (Kelley et al., 2000; Burt et al., 2008; Pecci et al., 2008; Balduini et al., 2011). The gene discussed is MYH9; the disease is macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss.