CDKN1C and neoplasm: In neoplasia, downregulation of p57Kip2 promotes cell migration, and invasion in human nasopharyngeal carcinoma cells [41] and decreased expression were associated with poor postsurgical survival time and lymphatic metastasis in lung cancer [42] as well as in other cancer types [25,39], e.g., in hepatocellular [43] or pancreatic [27] carcinoma.