TGFB3 and cleft palate: Mutations in the human TGFB3 have been linked to cleft palate (Lidral et al., 1998; Carinci et al., 2007), and a recent report described a disease-causing mutation in the coding region of TGFB3 in patients showing abnormalities in palate and muscle development (Rienhoff et al., 2013).