TNF and Familial prostate cancer: Other cell types that were analyzed are prostate cancer lines, where 1α,25(OH)2D3 reduced basal TNFα mRNA expression (Golovko et al., 2005), or 1α,25(OH)2D3/IL-1β-stimulated synoviocytes, where TNFα mRNA was decreased (Feng et al., 2013).