Recently, we have reported the reduced DcR1 (TNF-related apoptosis-inducing-ligand receptor-3) levels in AMD patients (Anand et al., 2014) where the angiogenic factors like CCR-3, VEGFR2, and eotaxin-2 (Sharma et al., 2012a,b, 2013a) were found to be increased in serum of these patients. The gene discussed is KDR; the disease is age-related macular degeneration.