To study the HERG1 role in pancreatic cancer cell lines, siRNA silencing of HERG1 was applied and stable HERG1 siRNA transfected cell lines (PANC-1/HERG1 siRNA, CFPAC-1/HERG1 siRNA) were established (Fig. 2A). Here, KCNH2 is linked to pancreatic neoplasm.