Furthermore, to examine whether HERG1 is linked to the pancreatic cancer progression in vivo, CFPAC-1, CFPAC-1/NC siRNA and CFPAC-1/HERG1 siRNA cells were injected into the left flank or pancreatic capsule of 4-week-old female BALB/c nu/nu mice. Here, KCNH2 is linked to familial pancreatic carcinoma.