NFE2L2 and cancer: Since Nrf-2 could regulate the expression of p73 by binding to P1 and P2 promoter, we performed immunohistochemistry staining (IHC staining) using a tissue microarray to further explore the particular relationship of TAp73, ΔNp73 and Nrf-2 expression in the malignant tumor and corresponding surrounding noncancerous tissues (NCTs) samples from 55 patients with breast cancer (Supplementary Table S1).