Elevated BIRC6 expression also correlated positively with poor prognostic factors such as PSA recurrence (Fig. 1B), lymph node metastasis (Fig. 1C) and prostatic capsule invasion (Fig. 1D) (p = 0.0571, 0.0286 and 0.0246, respectively, Chi square test for trend), indicative of its association with more advanced prostate cancer. Here, BIRC6 is linked to Familial prostate cancer.