The expression of survivin was also elevated in prostate cancer specimens (p = 0.004, Benign to T3-4), and correlated similar to BIRC6 with the above poor prognostic factors (p = 0.0167, PSA recurrence; p = 0.028, capsule invasion; p = 0.006, lymph node metastasis). This evidence concerns the gene BIRC6 and metastatic malignant neoplasm in the lymph nodes.