FGFR3 and breast cancer: Recent profiling reports have revealed invasive high-grade UCC can be clustered according to genes reflecting FGFR3 status (including papillary histology and FGFR3 related microRNAs), those seen in luminal breast cancer, and epithelial lineage and stem/progenitor cytokeratins (including a proportion of tumors with squamous histology) [8].