However, the prevalence of G6PD deficiencies, which ranges from < 0.1% to > 15%, can significantly influence the population normal value.4 Robust G6PD reference normal values for a given population can only be obtained using large sample numbers, but this is not feasible for evaluation studies of tests for G6PD deficiency. The gene discussed is G6PD; the disease is hyperinsulinemic hypoglycemia, familial, 4.