Ramp2 [Receptor (calcitonin) activity modifying protein 2], Acaa2 (Acetyl-Coenzyme A acyltransferase 2), Mdh1 (Malate dehydrogenase 1, NAD), and Tspan8 (Tetraspanin 8) are enriched mRNAs in the lungs and are involved in lung disease [28,29]. This evidence concerns the gene MDH1 and lung disorder.