Pearson correlation analysis revealed that the expression level of ISL-1 protein is strongly correlated with p-STAT3, p-c-Jun and c-Myc protein levels in human NHL samples surveyed (Pearson correlation coefficient r = 0.737, 0.501, 0.803 respectively, all p < 0.001). The gene discussed is STAT3; the disease is non-Hodgkin lymphoma.