Consequently, GCDFP-15 was also differentially distributed among biological tumor types, as defined by HR and HER2 status: frequency of positive tumors was significantly higher in luminal subtypes (HR+/HER2-: 42.4%, HR+/HER2: 45.6%) as well in HER2 positive tumors (HR-/HER2+: 55.8%) as opposed to in triple negative breast carcinomas (TNBC, HR-/HER2-: 26.2%, p = 0.001, Table 1). The gene discussed is ERBB2; the disease is neoplasm.