The results indicated that TCAB1 was significantly overexpressed in NPC cell line CNE1, OSCC cell lines HSC-3 and Cal-27, and also in ACC cell line ACC2, while the expression level was relatively low in human primary normal cells, including human periodontal ligament cells (PDLC) and human dental pulp cells (DPC) (Figure 1a, b). This evidence concerns the gene WRAP53 and nasopharyngeal carcinoma.