HIF1A and breast neoplasm: To examine the clinical relevance of miR-18a mediated HIF1A inhibition, we investigated the relationship between miR-18a and HIF1A mRNA levels in human breast tumor specimens by analyzing four data sets that contain both mRNA and miRNA expression data, which are available from TCGA or in the GEO database [GEO:GSE19783, GEO:GSE22220, GEO:GSE28884] [30–33].