The baseline urine IL-18 in patients with AKI (mean: 123.92 ± 87.61) did not differ (P = 0.21, Mann-Whitney test) from those who were controls (mean: 92.81 ± 43.54) and so with adjusted IL-18 (median: 124.07 and IQR: 49.6 to 180.67 with AKI and median: 98.44 and IQR: 72 to 129.4 for controls, P = 0.58, Mann- Whitney test). This evidence concerns the gene IL18 and acute kidney injury.