LCN2 and acute kidney injury: Twenty-four hours NGAL + IL-18 detected AKI in 72% (95% CI, 50.4% to 87.1%), and 24 hours NGAL + creatinine detected AKI in 80% (95% CI, 58.7% to 92.4%) (P = 0.51, comparison of proportions).Twenty-four hours NGAL alone detected AKI in 72% (95% CI, 50.4% to 87.1%), whereas 24 hours IL-18 alone detected AKI in 48% (95% CI, 28.3% to 68.3%) (P = 0.08, comparison of proportions).