MAPT and Alzheimer disease: Tau protein aggregation is found in several types of neurodegenerative diseases collectively termed “tauopathy,” which includes Alzheimer’s disease (AD), frontotemporal lobar degeneration chromosome 17, Pick’s disease, corticobasal degeneration, and the progressive supranuclear palsy (Brunden et al., 2009; Iqbal et al., 2005).