CADM1 and neoplasm: Using logistic regression, thereby allowing for the controlling of confounders (alcohol use, tumor size, lymph node status, and smoking), patients positive for HPV16 had increased hypermethylated CADM1 (OR = 19.3, CI = 7.5–49.3) or TIMP3 (OR = 5.9, CI = 2.3–15.6).