Among 1,495 veterans at four VA medical centers who underwent radical prostatectomy for prostate cancer in 1988–2007, including 206 classified in the electronic medical record as having been exposed to Agent Orange and 1,289 classified as unexposed, exposed patients were significantly more likely to be younger at the time of radical prostatectomy, have lower-stage disease, and have a lower preoperative PSA level [99]. This evidence concerns the gene KLK3 and Familial prostate cancer.