Due to these limitations, we screened, for the first time, the entire exonic region of GRM1 gene including flanking 5′- and 3′-UTRs and exon-intron junctions in ten commonly used PCa cell lines including the two established AA-PCa cell lines (E006AA and MDA-PCa2B), and 21 matched prostate tumor-normal tissues from 11 CAs and 10 AAs patients. This evidence concerns the gene GRM1 and posterior cortical atrophy.