NDRG2 and breast cancer: To determine the effect of NDRG2 overexpression on glucose deprivation-induced cell death, we first established stable clones of MDA-MB-231 breast cancer cells following transfection with the pCMV-Taq-2B (mock) or pCMV-Taq-2B-NDRG2 (NDRG2) plasmids.