In accordance to the findings from SiHa and HeLa cells, Wnt, Notch and STAT3 co-activations could be detected in 79.1% (34/43) of squmous cell carcinomas and 80% (20/25) of adenocarcinomas, suggesting their potential crosstalk in regulating cancer-related gene expression during the stepwise cervical carcinogenisis [46,47]. Here, STAT3 is linked to adenocarcinoma.