NR4A1 and neoplasm: The aim of the present study was to investigate the association between prediagnostic T3 levels and prognostic factors related to breast cancer aggressiveness; i.e. tumour size, grade, lymph node metastases, and hormonal receptor status.This was studied in a prospective cohort of 2185 women, out of whom 149 were diagnosed with invasive breast cancer during a follow-up of at least 18 years.