KPNA2 and hepatocellular carcinoma: It is noteworthy that the differential prognosis between PLAG1-negative HCC patients with positive or negative KPNA2 staining shows no significance (Figure 5a, RFS: KpPn vs KnPn, p = 0.226; Figure 5b, OS: KpPn vs KnPn, p = 0.438), confirming the clinical importance of PLAG1 for the role of KPNA2 in HCC.