To determine the in vivo interaction and clinical significance of KPNA2 and PLAG1, we performed an immunohistochemical analysis of KPNA2 and PLAG1 in a tissue microarray including 314 HCC patients with tumoral (T) and corresponding non-tumoral (NT) in separate section (Table 1). This evidence concerns the gene KPNA2 and hepatocellular carcinoma.