This suicide system utilizes a combination of the bacterial enzyme nitroreductase (Ntr) and the prodrug metronidazole (Met) that has been used to model other diseases in zebrafish [27]–[30], such as type 1 diabetes, where Ntr-expressing β cells in the pancreas were ablated with Met treatment [28]. Here, NTSR1 is linked to type 1 diabetes mellitus.