For the optimal cutoff of 0.266 × 109 eosinophils/L and 167 U/L of IgE levels, the area under the ROC curve showed similar values between eosinophils count and IgE levels in the diagnosis of helminthiasis (69% [95% CI 63%–74%] vs 67% [95% CI 60%–72%], P = 0.24), respectively. Here, IGHE is linked to helminthiasis.