Despite the considerable heterogeneity of the response, a focus on the top markers listed in Table S1 in File S1 confirms that several genes linked to changes in liver swelling, or hepatomegaly (e.g., ZDHHC2, AQP7, IL33), centrilobular hepatic eosinophilia, peroxisome proliferation (e.g.,HDC, ACSL3), hepatocellular hypertrophy (e.g., ACOT1, STAC3, CPT1B) and hepatic lipid accumulation (HSPB1, LRP1, NOL3) were differentially regulated. The gene discussed is HDC; the disease is Increased total eosinophil count.