PTEN and neoplasm: To determine the expression levels of miR-21 and Pten protein in tumor tissues from human NSCLC patients, we assessed 47 pairs of cancer tumor specimens and adjacent normal tissues (Table S1) by qRT-PCR and found a significantly higher expression of miR-21 in 37/47 (78.7%) in tumor tissues in comparison with adjacent normal tissues (Fig. 1A).