Moreover, disease relevance analysis showed that genes in the T4-2 differential network are associated with various cancers, such as small cell lung cancer, renal cell carcinoma, colorectal cancer, among others (Figure 5B, Table S3B), and that genes involved in the pathways such as ErbB and MAPK signaling pathways, focal adhesion, and ECM-receptor interaction (Table S1B) have significant association with pathways in cancer (FDR adjusted p-values<0.1). Here, EGFR is linked to cancer.