Further, genes in the EGFR/ITGB1-T4R differential network are connected with various cancers, including prostate, and small cell lung cancer (Figure 5C, Table S3C), suggesting that despite phenotypic reversion to normal, some malignant genes remain active in the EGFR/ITGB1-T4R cells. The gene discussed is ITGB1; the disease is cancer.