One study that examined two families with a partial WS phenotype, including supravalvular aortic stenosis (SVAS) and deficits in visuospatial construction, found that affected family members were hemizygous for the elastin (ELN) and LIM-Kinase1 (LIMK1) genes [13], which lie within the WSCR. Here, ELN is linked to supravalvular aortic stenosis.