Serologic tests for syphilis (RPR and Treponema/TP-PA), EBV-VCA IgM, toxoplasmosis (IgG and IgM) and search for cryptoccoccal antigen were negative.The patient had positive results for EBV–EBNA-1 IgG, CMV IgG, hepatitis C (anti HCV), hepatitis A, anti HBs, antiHBc. This evidence concerns the gene CD40LG and syphilis.