HNF1A and hypertensive disorder: Notably, the tests for the association of these variants with the classical CAD/MI risk traits also implicated the rs2259820_T (1.14 (1.03–1.26); P = 0.011) and rs2464196_C (1.12 (1.02–1.24); P = 0.024) further in T2DM (2550 versus 2081), as well as the rs2393791_T (1.14 (1.01–1.28); P = 0.032), rs7310409_G (1.16 (1.03–1.30); P = 0.013), and rs2464196_AG+GG (1.25 (1.05–1.49); P = 0.012) in HTN (3528 versus 1103), following adjustment for possible confounding effects of coexisting disease traits and other covariates (HNF1a Supplementary Data 4).