TET2 and myelodysplastic syndrome: A comparison of TET2 mutant CMML and MDS samples found that the peripheral monocyte count correlated with the proportion of TET2 mutated CD34+/CD38− cells, suggesting that the extent of dominance of the TET2 mutated clone in the HSC/MPP compartment influences the clinical phenotype (Itzykson et al., 2013).