EGF and neoplasm: This has allowed us to redefine their crucial interplay on the regulatory function between inflammatory and tumor cells [44,45,46,47] by means of the release of various granule-associated mediators (tryptase, chymase, tumour necrosis factor (TNF), VEGF, FGF, PDGF-β, epidermal growth factor (EGF)), lipid-derived mediators (leukotrienes, prostaglandins), cytokines (transforming growth factor-β (TGF-β), interleukins), and chemokines [48,49,50,51].