KIT and renal cell carcinoma: Over the years, several authors had examined c-Kit/c-KitR expression in different histological subtypes of RCC [31,32,33,34,35,36,37,38,39] all concluding that the chromophobe variety (and also the oncocytoma among benign renal tumors) had frequent c-KitR expression of strong [9,31] or moderate [32] intensity in immunohistochemistry (IHC) compared to other malignant histological subtypes, such as papillary and clear cell [31,32,33,34,35,36,37,38,39] (Table 1).