PIK3CA and neoplasm: Of the 390 patient cases, 338 were from the primary tumor site (86.7%), 37 from a metastatic site (9.5%), and the site was not specified in 15 patient cases (3.8%); in the population who gave consent for PIK3CA analysis, the overall percentages were consistent with the population with tissue evaluable for biomarker analyses (specimen site out of 274 patient cases, 270 were primary (87.6%), 26 were metastatic (9.5%), and 8 were not specified (2.9%)).