MPO and glomerulonephritis: Intriguingly, they also demonstrated that rabbit anti-human LAMP2-IgG (which cross-reacts with rat LAMP2) could induce a pauci-immune glomerulonephritis on passive antibody transfer into Wistar Kyoto (WKY) rats and that LAMP2-IgG could activate primed neutrophils and cause apoptosis in cultured endothelial cells in much the same way as the ‘classical’ ANCA MPO- and PR3-IgG had been shown to do [31].