APOE and atherosclerosis: The main result from the present study was that quantification of in vivo high resolution, small animal-dedicated PET/CT images of aortic FDG uptake in the apoE−/− murine model of atherosclerosis was dependent upon periaortic brown adipose tissue FDG uptake despite favorable, >>1 lesion-to-blood and lesion-to-lesion-free aortic wall tracer activity ratios as assessed by ex vivo analysis.