Post hoc LSD test gave significant differences between the KC and the healthy group (−15.0%, P < 0.000), the CCC and the healthy group (−18.6%, P < 0.000), the KC and the PRK group (−9.3%, P < 0.047), and the CCC and the PRK group (−13.1%, P < 0.009). The gene discussed is PLK3; the disease is keratoconus.