Post hoc LSD test gave significant differences between the KC and the healthy group (+10.0%, P < 0.003), the CCC and the healthy group (+16.7%, P < 0.000), the KC and the PRK group (+8.8%, P < 0.031), and the CCC and the PRK group (+15.4%, P < 0.000). The gene discussed is PLK3; the disease is keratoconus.