Previously, Cejka et al. found that patients with CKD stage 5 on dialysis showed higher sclerostin levels than patients without CKD (2055 ± 1239 pg/mL in CKD 5 patients on dialysis; 480 ± 150 pg/mL in premenopausal women; 1160 ± 380 pg/mL in postmenopausal women) [8, 10]. Here, SOST is linked to chronic kidney disease.