LARP7 and metastatic malignant neoplasm: LARP7 was expressed at relatively high levels in the untransformed mammary epithelial cell lines (MCF10A and EpH4) and noninvasive breast cancer cell lines (MCF7, BT474, T74D, and ZR75B), but was markedly reduced in all four invasive and metastatic cancer lines examined (MDA-MB-468, BT549, MDA-MB-231, and MDA-MB-435; Figure 1D).