MAPT and Parkinson disease: Another region that emerged with consistent evidence from regional FST and XP-EHH was found on chromosome 17 between 41.3 Mb and 41.5 Mb (Additional file1: Figure S1) and encompassed three genes, two of which (STH and KANSL1) have previously been implicated with variation in intracranial volume[21] and the microtubule-associated protein tau (MAPT) gene has been consistently reported to be associated with Parkinson’s disease in Europeans[22-24].