It is implausible that blood loss is responsible for this change since hematocrits were similar among all the AKI groups 24 h postprocedure; it is also implausible that other factors such as a change in erythropoietin production would only be evident at 7 days in one of the four AKI groups (the 500 μL group), especially since creatinine levels were similar in the 100 and 500 μL group. Here, EPO is linked to acute kidney injury.