As shown in Figure 8, no significant differences were observed among 100, 500, 1000, and 2000 μL fluid administration at 24 h post‐AKI regarding hematocrit, serum creatinine, BUN, ATN scores, lung neutrophils, lung MPO activity, or lung CXCL1, thus confirming that the severity of AKI and lung inflammation were similar 24 h post‐AKI among the four group, yet the two groups with delayed recovery of AKI (100 and 500 μL had increased lung inflammation at 7 days). Here, MPO is linked to acute kidney injury.