For lymph node metastasis, ten CpGs from six genes were found to be significant: CDH1 (site 10), CDH13 (sites 7 and 8), MINT3 (sites 3 and 4), CXCL12 (sites 1 and 3), RARB (site 6) and APC (sites 1 and 6) (Table 2). This evidence concerns the gene CDH1 and metastatic malignant neoplasm in the lymph nodes.