For example, we found Egfr to be interconnected in various dysregulated molecular pathways represented by different functional clusters including the calcium signaling pathway, neuroactive ligand-receptor interaction and the MAPK signaling pathway, as well as pathways in cancers such as pancreatic and colorectal cancers, which involve focal adhesion and regulation of actin cytoskeleton (Figure 3). The gene discussed is EGFR; the disease is colorectal cancer.