Amongst macrophages maintained with normoxic MDA-MB-231 and MCF-7 cells CM, only 6.94% and 5.24 % macrophages expressed CD206 respectively, while 39.5 and 37.07 % macrophages expressed CD206 when maintained in hypoxia (3hrs) primed breast cancer cells (MDA-MB231 and MCF-7) CM, which further escalated to 50.06% and 54.26 % respectively when duration of hypoxia was increased to 6hrs. The gene discussed is MRC1; the disease is breast carcinoma.