The results revealed an increase (~5 fold as a mean) in p27 mRNA in CLL samples, as compared to controls (tonsil and peripheral blood B lymphocytes) (Figure 1A) The analysis of the mRNA data loaded in the Oncomine databank (www.oncomine.org) revealed a high heterogeneity among different studies. Here, CDKN1B is linked to B-cell chronic lymphocytic leukemia.