Specifically, He et al (16) recorded a 25% inhibition of CT-26 colon tumors upon treatment with either ISO-1 or anti-MIF Abs administered twice per week, whereas Ogawa et al (40) reported a much higher inhibition (55%) of the same tumor upon a more frequent (every other day) treatment with anti-MIF Abs. The gene discussed is MIF; the disease is neoplasm.