WNK2 and cancer: The downregulated DEGs were found as involved in 47 significantly enriched pathways, mainly including cell transfer-related pathways, such as: cell adhesion molecules and focal adhesion; cell growth-related pathways, such as WNT, transforming growth factor-β (TGF-β), mitogen-activated protein kinase (MAPK) and calcium signaling pathways; and cancer-related immune and inflammation pathways, such as the T-/B- cell receptor and the chemokine signaling pathways.