CCR5 and Parkinson disease: Rentzos and colleagues also report that circulating RANTES (Regulated on Activation, Normal T Cell Expressed and Secreted), which is a C-C beta-chemokine with strong chemoattractant activity for T lymphocytes and monocytes [87], was increased in PD patients, which indicates that the recruitment of T lymphocytes to sites of inflammation in the central nervous system of PD patients may be through the interaction of RANTES and its receptor CCR5.