In this study similar pattern with lower frequency of thalassemia and Hb E was observed in blood donors because Hb concentration in thalassemia carriers (α-thalassemia 1 trait, β-thalassemia trait, and Hb E-related syndromes) varies ranging from normal value to very slight anemia [7, 19, 20]. This evidence concerns the gene GSTM1 and anemia (phenotype).